ACAA2 (acetyl-CoA acyltransferase 2)

2014-11-01  

Identity

HGNC
LOCATION
18q21.1
LOCUSID
ALIAS
DSAEC
FUSION GENES

Other Information

Locus ID:

NCBI: 10449
MIM: 604770
HGNC: 83
Ensembl: ENSG00000167315

Variants:

dbSNP: 10449
ClinVar: 10449
TCGA: ENSG00000167315
COSMIC: ACAA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167315ENST00000285093P42765
ENSG00000167315ENST00000585948K7EJB1
ENSG00000167315ENST00000586100K7ER88
ENSG00000167315ENST00000586485K7EJ68
ENSG00000167315ENST00000587994A0A0B4J2A4
ENSG00000167315ENST00000589432K7EME0

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Fatty acid elongationKEGGko00062
Fatty acid degradationKEGGko00071
Valine, leucine and isoleucine degradationKEGGko00280
Fatty acid elongationKEGGhsa00062
Fatty acid degradationKEGGhsa00071
Valine, leucine and isoleucine degradationKEGGhsa00280
Metabolic pathwaysKEGGhsa01100
Fatty acid biosynthesis, elongation, mitochondriaKEGGhsa_M00085
beta-OxidationKEGGhsa_M00087
Fatty acid biosynthesis, elongation, mitochondriaKEGGM00085
beta-OxidationKEGGM00087
Fatty acid metabolismKEGGhsa01212
Fatty acid metabolismKEGGko01212
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Mitochondrial Fatty Acid Beta-OxidationREACTOMER-HSA-77289

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386565512024The oncogenic role and regulatory mechanism of ACAA2 in human ovarian cancer.0
386565512024The oncogenic role and regulatory mechanism of ACAA2 in human ovarian cancer.0
373101462023Negative correlation between acetyl-CoA acyltransferase 2 and cetuximab resistance in colorectal cancer.0
377983722023ACAA2 is a novel molecular indicator for cancers with neuroendocrine phenotype.0
373101462023Negative correlation between acetyl-CoA acyltransferase 2 and cetuximab resistance in colorectal cancer.0
377983722023ACAA2 is a novel molecular indicator for cancers with neuroendocrine phenotype.0
361629922022LncRNA RPL34-AS1 suppresses the proliferation, migration and invasion of esophageal squamous cell carcinoma via targeting miR-575/ACAA2 axis.5
361629922022LncRNA RPL34-AS1 suppresses the proliferation, migration and invasion of esophageal squamous cell carcinoma via targeting miR-575/ACAA2 axis.5
209722502011Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.25
209722502011Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.25
205717542010Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population.31
206799602010Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.13
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
205717542010Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population.31
206799602010Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.13

Citation

Dessen P

ACAA2 (acetyl-CoA acyltransferase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60069/js/lib/css/favicon/favicon-32x32.png