ACY3 (aminoacylase 3)

2014-11-01  

Identity

HGNC
ACY3
LOCATION
11q13.2
LOCUSID
91703
ALIAS
ACY-3,HCBP1

Other Information

Locus ID:

NCBI: 91703
MIM: 614413
HGNC: 24104
Ensembl: ENSG00000132744

Variants:

dbSNP: 91703
ClinVar: 91703
TCGA: ENSG00000132744
COSMIC: ACY3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132744ENST00000255082Q96HD9
ENSG00000132744ENST00000255082A0A024R5L2
ENSG00000132744ENST00000529256E9PRA7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Aflatoxin activation and detoxificationREACTOMER-HSA-5423646

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA166128187diastolic blood pressureDiseaseVariantAnnotationassociatedPD28353407
PA166128188systolic blood pressureDiseaseVariantAnnotationassociatedPD28353407
PA444552HypertensionDiseaseClinicalAnnotation, VariantAnnotationassociatedPD28353407
PA448499atenololChemicalVariantAnnotationassociatedPD28353407
PA448641bisoprololChemicalClinicalAnnotation, VariantAnnotationassociatedPD28353407

References

Pubmed IDYearTitleCitations
194864482009Identification of a novel protein binding to hepatitis C virus core protein.3
194864482009Identification of a novel protein binding to hepatitis C virus core protein.3

Citation

Dessen P

ACY3 (aminoacylase 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60129