AMY1B (amylase alpha 1B)

2014-11-01  

Identity

HGNC
AMY1B
LOCATION
1p21.1
LOCUSID
277
ALIAS
AMY1

Other Information

Locus ID:

NCBI: 277
MIM: 104701
HGNC: 475
Ensembl: ENSG00000174876

Variants:

dbSNP: 277
ClinVar: 277
TCGA: ENSG00000174876
COSMIC: AMY1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174876ENST00000330330P04745
ENSG00000174876ENST00000370080P04745
ENSG00000174876ENST00000425410Q5T084
ENSG00000174876ENST00000446703Q5T085

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Starch and sucrose metabolismKEGGko00500
Starch and sucrose metabolismKEGGhsa00500
Metabolic pathwaysKEGGhsa01100
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970
Carbohydrate digestion and absorptionKEGGko04973
Carbohydrate digestion and absorptionKEGGhsa04973
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Digestion of dietary carbohydrateREACTOMER-HSA-189085

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
326978252020AMY1 Gene Copy Number Correlates With Glucose Absorption and Visceral Fat Volume, but Not with Insulin Resistance.0
326978252020AMY1 Gene Copy Number Correlates With Glucose Absorption and Visceral Fat Volume, but Not with Insulin Resistance.0
309828602019Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.6
309828602019Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.6
282194102017Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity.17
282194102017Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity.17
255887012015Salivary alpha amylase diurnal pattern and stress response are associated with body mass index in low-income preschool-aged children.8
255887012015Salivary alpha amylase diurnal pattern and stress response are associated with body mass index in low-income preschool-aged children.8
220636482012Salivary alpha-amylase and cortisol responsiveness following electrical stimulation stress in major depressive disorder patients.14
220636482012Salivary alpha-amylase and cortisol responsiveness following electrical stimulation stress in major depressive disorder patients.14
218278212011State and trait variance in salivary α-amylase: a behavioral genetic study.10
218278212011State and trait variance in salivary α-amylase: a behavioral genetic study.10
161527702005On the genetic polymorphism of the serum alpha-amylase in the population of the south western Bulgaria (second communication).0
161527702005On the genetic polymorphism of the serum alpha-amylase in the population of the south western Bulgaria (second communication).0

Citation

Dessen P

AMY1B (amylase alpha 1B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60281