ARSK (arylsulfatase family member K)

2014-11-01  

Identity

HGNC
ARSK
LOCATION
5q15
LOCUSID
153642
ALIAS
TSULF

Other Information

Locus ID:

NCBI: 153642
MIM: 610011
HGNC: 25239
Ensembl: ENSG00000164291

Variants:

dbSNP: 153642
ClinVar: 153642
TCGA: ENSG00000164291
COSMIC: ARSK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164291ENST00000380009Q6UWY0
ENSG00000164291ENST00000504763D6R9F9
ENSG00000164291ENST00000504873E9PGI0
ENSG00000164291ENST00000512106H0Y9F6
ENSG00000164291ENST00000513814D6RBR4

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Gamma carboxylation, hypusine formation and arylsulfatase activationREACTOMER-HSA-163841
The activation of arylsulfatasesREACTOMER-HSA-1663150
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Sphingolipid metabolismREACTOMER-HSA-428157
Glycosphingolipid metabolismREACTOMER-HSA-1660662

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386346252024Further characterization of ARSK-related mucopolysaccharidosis type 10.0
386346252024Further characterization of ARSK-related mucopolysaccharidosis type 10.0
239864402013Arylsulfatase K, a novel lysosomal sulfatase.11
239864402013Arylsulfatase K, a novel lysosomal sulfatase.11
165000422006Molecular cloning and initial characterization of three novel human sulfatases.12
165000422006Molecular cloning and initial characterization of three novel human sulfatases.12

Citation

Dessen P

ARSK (arylsulfatase family member K)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60539