ATP6V0D1 (ATPase H+ transporting V0 subunit d1)

2014-11-01  

Identity

HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
ATP6D,ATP6DV,P39,VATX,VMA6,VPATPD
FUSION GENES

Other Information

Locus ID:

NCBI: 9114
MIM: 607028
HGNC: 13724
Ensembl: ENSG00000159720

Variants:

dbSNP: 9114
ClinVar: 9114
TCGA: ENSG00000159720
COSMIC: ATP6V0D1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159720ENST00000290949P61421
ENSG00000159720ENST00000426604F8WEN9
ENSG00000159720ENST00000540149F5GYQ1
ENSG00000159720ENST00000561852H3BUQ0
ENSG00000159720ENST00000563064H3BTB5
ENSG00000159720ENST00000564191H3BSG7
ENSG00000159720ENST00000564615H3BQJ1
ENSG00000159720ENST00000564788H3BQB4
ENSG00000159720ENST00000565835J3QL14
ENSG00000159720ENST00000566322H3BPS0
ENSG00000159720ENST00000568101H3BTB4
ENSG00000159720ENST00000602876R4GN72

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Vibrio cholerae infectionKEGGko05110
Epithelial cell signaling in Helicobacter pylori infectionKEGGko05120
Oxidative phosphorylationKEGGhsa00190
Vibrio cholerae infectionKEGGhsa05110
Epithelial cell signaling in Helicobacter pylori infectionKEGGhsa05120
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Metabolic pathwaysKEGGhsa01100
Collecting duct acid secretionKEGGko04966
Collecting duct acid secretionKEGGhsa04966
PhagosomeKEGGko04145
PhagosomeKEGGhsa04145
Rheumatoid arthritisKEGGko05323
Rheumatoid arthritisKEGGhsa05323
TuberculosisKEGGko05152
TuberculosisKEGGhsa05152
Synaptic vesicle cycleKEGGko04721
Synaptic vesicle cycleKEGGhsa04721
V-type ATPase, eukaryotesKEGGhsa_M00160
V-type ATPase, eukaryotesKEGGM00160
Viral carcinogenesisKEGGhsa05203
Viral carcinogenesisKEGGko05203
Metabolism of proteinsREACTOMER-HSA-392499
Unfolded Protein Response (UPR)REACTOMER-HSA-381119
IRE1alpha activates chaperonesREACTOMER-HSA-381070
XBP1(S) activates chaperone genesREACTOMER-HSA-381038
ROS, RNS production in phagocytesREACTOMER-HSA-1222556
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Signaling by Insulin receptorREACTOMER-HSA-74752
Insulin receptor recyclingREACTOMER-HSA-77387
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Iron uptake and transportREACTOMER-HSA-917937
Transferrin endocytosis and recyclingREACTOMER-HSA-917977
Ion channel transportREACTOMER-HSA-983712

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366403292023ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.14
366403292023ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis.14
246319252014Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.0
246319252014Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli.0
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
191655272009Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.69
192859862009Control elements in the neighboring ATPase gene influence spatiotemporal expression of the human agouti-related protein.7
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
191655272009Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.69
192859862009Control elements in the neighboring ATPase gene influence spatiotemporal expression of the human agouti-related protein.7
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

ATP6V0D1 (ATPase H+ transporting V0 subunit d1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60636/gene-fusions-explorer/favicon/deep-insight-explorer/