BZW1 (basic leucine zipper and W2 domains 1)

2014-11-01  

Identity

HGNC
BZW1
LOCATION
2q33.1
LOCUSID
9689
ALIAS
BZAP45,Nbla10236
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9689
HGNC: 18380
Ensembl: ENSG00000082153

Variants:

dbSNP: 9689
ClinVar: 9689
TCGA: ENSG00000082153
COSMIC: BZW1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000082153ENST00000359893H0Y503
ENSG00000082153ENST00000409226Q7L1Q6
ENSG00000082153ENST00000409600Q7L1Q6
ENSG00000082153ENST00000409600A0A024R3Z6
ENSG00000082153ENST00000410110C9IZ80
ENSG00000082153ENST00000419090C9JWF5
ENSG00000082153ENST00000447069C9JV57
ENSG00000082153ENST00000450637C9J188
ENSG00000082153ENST00000452206C9JFN4
ENSG00000082153ENST00000452790Q7L1Q6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383065702024BZW1 is a prognostic and immunological biomarker in pancreatic adenocarcinoma.1
385014212024[Overexpression of BZW1 promotes invasion and metastasis of gastric cancer cells by regulating Wnt/β-catenin signaling and promoting epithelial-mesenchymal transition].0
383065702024BZW1 is a prognostic and immunological biomarker in pancreatic adenocarcinoma.1
385014212024[Overexpression of BZW1 promotes invasion and metastasis of gastric cancer cells by regulating Wnt/β-catenin signaling and promoting epithelial-mesenchymal transition].0
378284272023Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice.1
378284272023Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice.1
349519952022BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2α Phosphorylation.25
349519952022BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2α Phosphorylation.25
333935902021LncRNA NEAT1 promotes glioma cancer progression via regulation of miR-98-5p/BZW1.18
338864192021BZW1 promotes cell proliferation in prostate cancer by regulating TGF-β1/Smad pathway.7
333935902021LncRNA NEAT1 promotes glioma cancer progression via regulation of miR-98-5p/BZW1.18
338864192021BZW1 promotes cell proliferation in prostate cancer by regulating TGF-β1/Smad pathway.7
329455052020Long non‑coding RNA NEAT1 modifies cell proliferation, colony formation, apoptosis, migration and invasion via the miR‑4500/BZW1 axis in ovarian cancer.16
329455052020Long non‑coding RNA NEAT1 modifies cell proliferation, colony formation, apoptosis, migration and invasion via the miR‑4500/BZW1 axis in ovarian cancer.16
316018332019Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis.9

Citation

Dessen P

BZW1 (basic leucine zipper and W2 domains 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60847/gene-fusions-explorer/case-report-explorer/teaching-explorer/js/lib/zoomerang.js