Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8574
MIM: 603418
HGNC: 389
Ensembl: ENSG00000053371
Variants:
dbSNP: 8574
ClinVar: 8574
TCGA: ENSG00000053371
COSMIC: AKR7A2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA449212 | daunorubicin | Chemical | VariantAnnotation | associated | PK | 20837989 | |
| PA449412 | doxorubicin | Chemical | VariantAnnotation | associated | PK | 20837989 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30817976 | 2019 | Insights into the transcriptional regulation of the anthracycline reductase AKR7A2 in human cardiomyocytes. | 2 |
| 30817976 | 2019 | Insights into the transcriptional regulation of the anthracycline reductase AKR7A2 in human cardiomyocytes. | 2 |
| 28536627 | 2016 | The identification of human aldo-keto reductase AKR7A2 as a novel cytoglobin-binding partner. | 2 |
| 28536627 | 2016 | The identification of human aldo-keto reductase AKR7A2 as a novel cytoglobin-binding partner. | 2 |
| 25027672 | 2015 | GST-M1 is transcribed moreso than AKR7A2 in AFB₁-exposed human monocytes and lymphocytes. | 4 |
| 25451587 | 2015 | Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2. | 9 |
| 25027672 | 2015 | GST-M1 is transcribed moreso than AKR7A2 in AFB₁-exposed human monocytes and lymphocytes. | 4 |
| 25451587 | 2015 | Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2. | 9 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 21044367 | 2010 | An integrative method for scoring candidate genes from association studies: application to warfarin dosing. | 11 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 21044367 | 2010 | An integrative method for scoring candidate genes from association studies: application to warfarin dosing. | 11 |
| 19077459 | 2009 | Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma. | 29 |
| 19077459 | 2009 | Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma. | 29 |
| 18752886 | 2008 | Genetic variation of Aflatoxin B1 aldehyde reductase genes (AFAR) in human tumour cells. | 3 |
Citation
Dessen P
AKR7A2 (aldo-keto reductase family 7 member A2)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/613/akr7a2
