CA3 (carbonic anhydrase 3)

2014-11-01  

Identity

HGNC
CA3
LOCATION
8q21.2
LOCUSID
761
ALIAS
CAIII,Car3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 761
MIM: 114750
HGNC: 1374
Ensembl: ENSG00000164879

Variants:

dbSNP: 761
ClinVar: 761
TCGA: ENSG00000164879
COSMIC: CA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164879ENST00000285381P07451
ENSG00000164879ENST00000285381V9HWA3
ENSG00000164879ENST00000520921E5RHI4

Expression (GTEx)

0
500
1000
1500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Nitrogen metabolismKEGGko00910
Nitrogen metabolismKEGGhsa00910
MetabolismREACTOMER-HSA-1430728
Reversible hydration of carbon dioxideREACTOMER-HSA-1475029

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
350164062021Carbonic anhydrase 2 and 3 as risk biomarkers for dilated cardiomyopathy associated heart failure.10
350164062021Carbonic anhydrase 2 and 3 as risk biomarkers for dilated cardiomyopathy associated heart failure.10
321830302020Carbonic Anhydrase III Promotes Cell Migration and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma.11
327775212020Carbonic anhydrase III is a new target of HIF1α in prostate cancer model.3
321830302020Carbonic Anhydrase III Promotes Cell Migration and Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma.11
327775212020Carbonic anhydrase III is a new target of HIF1α in prostate cancer model.3
295596612018Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death.20
295596612018Expression of Carbonic Anhydrase III, a Nucleus Pulposus Phenotypic Marker, is Hypoxia-responsive and Confers Protection from Oxidative Stress-induced Cell Death.20
268473022016Expression of CAIII and Hsp70 Is Increased the Mucous Membrane of the Posterior Commissure in Laryngopharyngeal Reflux Disease.5
268473022016Expression of CAIII and Hsp70 Is Increased the Mucous Membrane of the Posterior Commissure in Laryngopharyngeal Reflux Disease.5
248381802014Importance of tryptophan nitration of carbonic anhydrase III for the morbidity of atopic dermatitis.3
248381802014Importance of tryptophan nitration of carbonic anhydrase III for the morbidity of atopic dermatitis.3
239817572013Anti-carbonic anhydrase III autoantibodies in vasculitis syndrome.3
239817572013Anti-carbonic anhydrase III autoantibodies in vasculitis syndrome.3
227971482012Mass spectrometry-based proteomic analysis of middle-aged vs. aged vastus lateralis reveals increased levels of carbonic anhydrase isoform 3 in senescent human skeletal muscle.37

Citation

Dessen P

CA3 (carbonic anhydrase 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61341