CC2D1B (coiled-coil and C2 domain containing 1B)

2014-11-01  

Identity

HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
Lgd1
FUSION GENES

Other Information

Locus ID:

NCBI: 200014
HGNC: 29386
Ensembl: ENSG00000154222

Variants:

dbSNP: 200014
ClinVar: 200014
TCGA: ENSG00000154222
COSMIC: CC2D1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154222ENST00000284376Q5T0F9
ENSG00000154222ENST00000371586Q5T0F9
ENSG00000154222ENST00000438021H0Y517
ENSG00000154222ENST00000450942H7C1U3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
330340242021Unravelling of Hidden Secrets: The Tumour Suppressor Lethal (2) Giant Discs (Lgd)/CC2D1, Notch Signalling and Cancer.6
330340242021Unravelling of Hidden Secrets: The Tumour Suppressor Lethal (2) Giant Discs (Lgd)/CC2D1, Notch Signalling and Cancer.6
305133012018CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.40
305133012018CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope.40
277698582016CC2D1A and CC2D1B regulate degradation and signaling of EGFR and TLR4.5
277698582016CC2D1A and CC2D1B regulate degradation and signaling of EGFR and TLR4.5
194230802009Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression.20
194230802009Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression.20
170843582006The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking.62
170843582006The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking.62

Citation

Dessen P

CC2D1B (coiled-coil and C2 domain containing 1B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61455/js/css/template-nav.css