CPA3 (carboxypeptidase A3)

2014-11-01  

Identity

HGNC
CPA3
LOCATION
3q24
LOCUSID
1359
ALIAS
MC-CPA
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1359
MIM: 114851
HGNC: 2298
Ensembl: ENSG00000163751

Variants:

dbSNP: 1359
ClinVar: 1359
TCGA: ENSG00000163751
COSMIC: CPA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163751ENST00000296046P15088

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Renin-angiotensin systemKEGGko04614
Renin-angiotensin systemKEGGhsa04614
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Protein digestion and absorptionKEGGko04974
Protein digestion and absorptionKEGGhsa04974
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Metabolism of Angiotensinogen to AngiotensinsREACTOMER-HSA-2022377

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
340577532021Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin.24
340577532021Severe COVID-19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin.24
295120952019Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease.6
295120952019Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease.6
271573942016Genome-wide expression profiling in the peripheral blood of patients with fibromyalgia.23
271573942016Genome-wide expression profiling in the peripheral blood of patients with fibromyalgia.23
247269232014Tryptase-PAR2 axis in experimental autoimmune prostatitis, a model for chronic pelvic pain syndrome.28
247269232014Tryptase-PAR2 axis in experimental autoimmune prostatitis, a model for chronic pelvic pain syndrome.28
196436692009Novel insights into the biological function of mast cell carboxypeptidase A.37
196436692009Novel insights into the biological function of mast cell carboxypeptidase A.37
147607542004Cloning and expression of human colon mast cell carboxypeptidase.1
147607542004Cloning and expression of human colon mast cell carboxypeptidase.1

Citation

Dessen P

CPA3 (carboxypeptidase A3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62045