CPTP (ceramide-1-phosphate transfer protein)

2014-11-01  

Identity

HGNC
LOCATION
1p36.33
LOCUSID
ALIAS
GLTPD1

Other Information

Locus ID:

NCBI: 80772
MIM: 615467
HGNC: 28116
Ensembl: ENSG00000224051

Variants:

dbSNP: 80772
ClinVar: 80772
TCGA: ENSG00000224051
COSMIC: CPTP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000224051ENST00000343938Q5TA50
ENSG00000224051ENST00000343938S4S694
ENSG00000224051ENST00000488011J3KST3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Sphingolipid metabolismREACTOMER-HSA-428157
Glycosphingolipid metabolismREACTOMER-HSA-1660662

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
359829092022Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.4
359829092022Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.4
337817492021Ceramide-1-phosphate transfer protein (CPTP) regulation by phosphoinositides.2
344998822021Ceramide-1-phosphate and its transfer proteins in eukaryotes.4
337817492021Ceramide-1-phosphate transfer protein (CPTP) regulation by phosphoinositides.2
344998822021Ceramide-1-phosphate and its transfer proteins in eukaryotes.4
291649962018CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation.33
291649962018CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation.33
238639332013Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.100
238639332013Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.100
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

CPTP (ceramide-1-phosphate transfer protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62068/haematological-explorer/css/meetings/