CTIF (cap binding complex dependent translation initiation factor)

2014-11-01  

Identity

HGNC
LOCATION
18q21.1
LOCUSID
ALIAS
Gm672,KIAA0427
FUSION GENES

Other Information

Locus ID:

NCBI: 9811
MIM: 613178
HGNC: 23925
Ensembl: ENSG00000134030

Variants:

dbSNP: 9811
ClinVar: 9811
TCGA: ENSG00000134030
COSMIC: CTIF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134030ENST00000256413O43310
ENSG00000134030ENST00000256413A0A024R259
ENSG00000134030ENST00000382998O43310
ENSG00000134030ENST00000587752K7EK08
ENSG00000134030ENST00000588345K7EQS5
ENSG00000134030ENST00000591387K7EPK6
ENSG00000134030ENST00000591412K7EQS9

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
331035642021CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev.6
342329972021Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF-DDX19B interaction.8
331035642021CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev.6
342329972021Translation mediated by the nuclear cap-binding complex is confined to the perinuclear region via a CTIF-DDX19B interaction.8
297895352018Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets.17
297895352018Coupling bimolecular PARylation biosensors with genetic screens to identify PARylation targets.17
262640412015Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium.3
262640412015Association of SNPs in LCP1 and CTIF with hearing in 11 year old children: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort and the G-EAR consortium.3
218403102011Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2.11
218403102011Ago2/miRISC-mediated inhibition of CBP80/20-dependent translation and thereby abrogation of nonsense-mediated mRNA decay require the cap-associating activity of Ago2.11
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
196481792009A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation.63
196481792009A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation.63

Citation

Dessen P

CTIF (cap binding complex dependent translation initiation factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62184/js/lib/favicon/teaching-explorer/