ALPI (alkaline phosphatase, intestinal)

2003-11-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
IAP
FUSION GENES

Other Information

Locus ID:

NCBI: 248
MIM: 171740
HGNC: 437
Ensembl: ENSG00000163295

Variants:

dbSNP: 248
ClinVar: 248
TCGA: ENSG00000163295
COSMIC: ALPI

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163295ENST00000295463P09923
ENSG00000163295ENST00000295463A0A024R4A2
ENSG00000163295ENST00000457560F8WEQ0

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Thiamine metabolismKEGGko00730
Folate biosynthesisKEGGko00790
Thiamine metabolismKEGGhsa00730
Folate biosynthesisKEGGhsa00790
Metabolic pathwaysKEGGhsa01100
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PAREACTOMER-HSA-1483166
Miscellaneous digestion eventsREACTOMER-HSA-8935690

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
378702352024Effect of Surgery on Postoperative Levels of the Gut Homeostasis-Regulating Enzyme Intestinal Alkaline Phosphatase.1
378702352024Effect of Surgery on Postoperative Levels of the Gut Homeostasis-Regulating Enzyme Intestinal Alkaline Phosphatase.1
373009912023The role of intestinal alkaline phosphatase in the development of necrotizing enterocolitis.1
373009912023The role of intestinal alkaline phosphatase in the development of necrotizing enterocolitis.1
350821352022Intestinal alkaline phosphatase deficiency increases the risk of diabetes.4
356945412022Intestinal Alkaline Phosphatase Prevents Sulfate Reducing Bacteria-Induced Increased Tight Junction Permeability by Inhibiting Snail Pathway.6
360471002022Characterization and Structure of Alternatively Spliced Transcript Variant of Human Intestinal Alkaline Phosphatase (ALPI) Gene.1
350821352022Intestinal alkaline phosphatase deficiency increases the risk of diabetes.4
356945412022Intestinal Alkaline Phosphatase Prevents Sulfate Reducing Bacteria-Induced Increased Tight Junction Permeability by Inhibiting Snail Pathway.6
360471002022Characterization and Structure of Alternatively Spliced Transcript Variant of Human Intestinal Alkaline Phosphatase (ALPI) Gene.1
333914582021A role for intestinal alkaline phosphatase in preventing liver fibrosis.20
349444282021Role of Intestinal Alkaline Phosphatase in Innate Immunity.15
333914582021A role for intestinal alkaline phosphatase in preventing liver fibrosis.20
349444282021Role of Intestinal Alkaline Phosphatase in Innate Immunity.15
319154702019Intestinal Alkaline Phosphatase Deficiency Is Associated with Ischemic Heart Disease.5

Citation

Dessen P

ALPI (alkaline phosphatase, intestinal)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/622/gene-explorer/js/lib/teaching-explorer/