DYNLL2 (dynein light chain LC8-type 2)

2014-11-01  

Identity

HGNC
LOCATION
17q22
LOCUSID
ALIAS
DNCL1B,Dlc2,RSPH22
FUSION GENES

Other Information

Locus ID:

NCBI: 140735
MIM: 608942
HGNC: 24596
Ensembl: ENSG00000264364

Variants:

dbSNP: 140735
ClinVar: 140735
TCGA: ENSG00000264364
COSMIC: DYNLL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000264364ENST00000579991Q96FJ2

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Vasopressin-regulated water reabsorptionKEGGko04962
Vasopressin-regulated water reabsorptionKEGGhsa04962
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Intraflagellar transportREACTOMER-HSA-5620924
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Intrinsic Pathway for ApoptosisREACTOMER-HSA-109606
Activation of BH3-only proteinsREACTOMER-HSA-114452
Activation of BMF and translocation to mitochondriaREACTOMER-HSA-139910
Cellular responses to stressREACTOMER-HSA-2262752
MacroautophagyREACTOMER-HSA-1632852
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-independent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811436

References

Pubmed IDYearTitleCitations
253128462014DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity.10
253128462014DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity.10
208899822010Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms.18
208899822010Affinity, avidity, and kinetics of target sequence binding to LC8 dynein light chain isoforms.18

Citation

Dessen P

DYNLL2 (dynein light chain LC8-type 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62693/meetings/favicon/js/web-card-_common.js