FAM20C (FAM20C golgi associated secretory pathway kinase)

2014-11-01  

Identity

HGNC
FAM20C
LOCATION
7p22.3
LOCUSID
56975
ALIAS
DMP-4,DMP4,G-CK,GEF-CK,RNS
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56975
MIM: 611061
HGNC: 22140
Ensembl: ENSG00000177706

Variants:

dbSNP: 56975
ClinVar: 56975
TCGA: ENSG00000177706
COSMIC: FAM20C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177706ENST00000313766Q8IXL6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
367088082023Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma.2
369140452023Intracranial calcification in Fam20c-deficient mice recapitulates human Raine syndrome.0
367088082023Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma.2
369140452023Intracranial calcification in Fam20c-deficient mice recapitulates human Raine syndrome.0
333061212021Prognostic and immunological role of Fam20C in pan-cancer.17
337597832021The ABCs of the atypical Fam20 secretory pathway kinases.16
343490202021Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization.7
343608052021FAM20C Overview: Classic and Novel Targets, Pathogenic Variants and Raine Syndrome Phenotypes.11
344335852021Fam20C Regulates Bone Resorption and Breast Cancer Bone Metastasis through Osteopontin and BMP4.15
333061212021Prognostic and immunological role of Fam20C in pan-cancer.17
337597832021The ABCs of the atypical Fam20 secretory pathway kinases.16
343490202021Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization.7
343608052021FAM20C Overview: Classic and Novel Targets, Pathogenic Variants and Raine Syndrome Phenotypes.11
344335852021Fam20C Regulates Bone Resorption and Breast Cancer Bone Metastasis through Osteopontin and BMP4.15
320932342020Two Novel FAM20C Variants in A Family with Raine Syndrome.6

Citation

Dessen P

FAM20C (FAM20C golgi associated secretory pathway kinase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63130