FAR2 (fatty acyl-CoA reductase 2)

2014-11-01  

Identity

HGNC
LOCATION
12p11.22
LOCUSID
ALIAS
HEL-S-81,MLSTD1,SDR10E2
FUSION GENES

Other Information

Locus ID:

NCBI: 55711
MIM: 616156
HGNC: 25531
Ensembl: ENSG00000064763

Variants:

dbSNP: 55711
ClinVar: 55711
TCGA: ENSG00000064763
COSMIC: FAR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000064763ENST00000182377Q96K12
ENSG00000064763ENST00000182377A0A024RAW7
ENSG00000064763ENST00000536681Q96K12
ENSG00000064763ENST00000536681A0A024RAW7
ENSG00000064763ENST00000547116Q96K12
ENSG00000064763ENST00000547759H0YHP1
ENSG00000064763ENST00000551193H0YIE0
ENSG00000064763ENST00000551451F8VPF2
ENSG00000064763ENST00000552137F8VX60

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Wax biosynthesisREACTOMER-HSA-8848584

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
296526352018FAR2 is associated with kidney disease in mice and humans.9
296526352018FAR2 is associated with kidney disease in mice and humans.9
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
152203482004Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.106
152203492004Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.44
152203482004Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions.106
152203492004Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family.44

Citation

Dessen P

FAR2 (fatty acyl-CoA reductase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63295/tumors-explorer/gene-fusions-explorer/