GADL1 (glutamate decarboxylase like 1)

2014-11-01 Affiliation

Identity

HGNC

GADL1

LOCATION

3p24.1

LOCUSID

339896

ALIAS

ADC,CSADC,HuADC,HuCSADC

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 339896
MIM: 615601
HGNC: 27949
Ensembl: ENSG00000144644

Variants:

dbSNP: 339896
ClinVar: 339896
TCGA: ENSG00000144644
COSMIC: GADL1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000144644	ENST00000282538	Q6ZQY3
ENSG00000144644	ENST00000454381	Q6ZQY3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
beta-Alanine metabolism	KEGG	ko00410
Taurine and hypotaurine metabolism	KEGG	ko00430
Pantothenate and CoA biosynthesis	KEGG	ko00770
beta-Alanine metabolism	KEGG	hsa00410
Taurine and hypotaurine metabolism	KEGG	hsa00430
Pantothenate and CoA biosynthesis	KEGG	hsa00770
Metabolic pathways	KEGG	hsa01100
Metabolism	REACTOME	R-HSA-1430728
Metabolism of amino acids and derivatives	REACTOME	R-HSA-71291
Amino acid synthesis and interconversion (transamination)	REACTOME	R-HSA-70614

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
30923325	2019	Effects of GADL1 overexpression on cell migration and the associated morphological changes.	3
30923325	2019	Effects of GADL1 overexpression on cell migration and the associated morphological changes.	3
28214779	2017	Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders.	3
28214779	2017	Lithium response in bipolar disorder: No difference in GADL1 gene expression between cell lines from excellent-responders and non-responders.	3
25415457	2015	GADL1 gene polymorphisms and lithium response in bipolar I disorder: lack of association from an Indian population.	9
26327310	2015	Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.	13
25415457	2015	GADL1 gene polymorphisms and lithium response in bipolar I disorder: lack of association from an Indian population.	9
26327310	2015	Mammalian CSAD and GADL1 have distinct biochemical properties and patterns of brain expression.	13
24369049	2014	Variant GADL1 and response to lithium therapy in bipolar I disorder.	47
24369049	2014	Variant GADL1 and response to lithium therapy in bipolar I disorder.	47

Citation

Dessen P

GADL1 (glutamate decarboxylase like 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/63659/js/gene-fusions/gene-explorer/