ANGPTL1 (angiopoietin like 1)

2003-02-01  

Identity

HGNC
LOCATION
1q25.2
LOCUSID
ALIAS
ANG3,ANGPT3,ARP1,AngY,UNQ162,dJ595C2.2

Other Information

Locus ID:

NCBI: 9068
MIM: 603874
HGNC: 489
Ensembl: ENSG00000116194

Variants:

dbSNP: 9068
ClinVar: 9068
TCGA: ENSG00000116194
COSMIC: ANGPTL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116194ENST00000234816O95841
ENSG00000116194ENST00000234816A0A024R908
ENSG00000116194ENST00000367629O95841
ENSG00000116194ENST00000367629A0A024R908
ENSG00000116194ENST00000444255A0A0A0MSK1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381508912024Exosome-transmitted ANGPTL1 suppresses angiogenesis in glioblastoma by inhibiting the VEGFA/VEGFR2/Akt/eNOS pathway.0
381508912024Exosome-transmitted ANGPTL1 suppresses angiogenesis in glioblastoma by inhibiting the VEGFA/VEGFR2/Akt/eNOS pathway.0
354754762022ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer.6
354754762022ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer.6
330976732021Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis.3
334135362021Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.49
330976732021Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis.3
334135362021Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.49
311032652019Long non-coding RNA ANGPTL1-3 promotes multiple myeloma bortezomib resistance by sponging miR-30a-3p to activate c-Maf expression.10
311032652019Long non-coding RNA ANGPTL1-3 promotes multiple myeloma bortezomib resistance by sponging miR-30a-3p to activate c-Maf expression.10
286061302017ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138.17
286061302017ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138.17
268296022016Aberrant expression of angiopoietin-like proteins 1 and 2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.6
268296022016Aberrant expression of angiopoietin-like proteins 1 and 2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.6
259704672015Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis.14

Citation

Dessen P

ANGPTL1 (angiopoietin like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/639/favicon/cancer-prone-explorer/js/web-card-gene.js