GPR75 (G protein-coupled receptor 75)

2014-11-01  

Identity

HGNC
GPR75
LOCATION
2p16.2
LOCUSID
10936
ALIAS
GPRchr2,WI31133

Other Information

Locus ID:

NCBI: 10936
MIM: 606704
HGNC: 4526
Ensembl: ENSG00000119737

Variants:

dbSNP: 10936
ClinVar: 10936
TCGA: ENSG00000119737
COSMIC: GPR75

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119737ENST00000394705O95800

Expression (GTEx)

0
1
2
3
4
5
6
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
372473052023G Protein-Coupled Receptor 75 (GPR75) As a Novel Molecule for Targeted Therapy of Cancer and Metabolic Syndrome.4
372473052023G Protein-Coupled Receptor 75 (GPR75) As a Novel Molecule for Targeted Therapy of Cancer and Metabolic Syndrome.4
339742692021Uncovering the signalling, structure and function of the 20-HETE-GPR75 pairing: Identifying the chemokine CCL5 as a negative regulator of GPR75.15
342108522021Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.94
339742692021Uncovering the signalling, structure and function of the 20-HETE-GPR75 pairing: Identifying the chemokine CCL5 as a negative regulator of GPR75.15
342108522021Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity.94
317600762020GPR75 receptor mediates 20-HETE-signaling and metastatic features of androgen-insensitive prostate cancer cells.15
317600762020GPR75 receptor mediates 20-HETE-signaling and metastatic features of androgen-insensitive prostate cancer cells.15
297720592018The orphan G-protein-coupled receptor 75 signaling is activated by the chemokine CCL5.23
297720592018The orphan G-protein-coupled receptor 75 signaling is activated by the chemokine CCL5.23

Citation

Dessen P

GPR75 (G protein-coupled receptor 75)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64004