GPRC5B (G protein-coupled receptor class C group 5 member B)

2014-11-01  

Identity

HGNC
GPRC5B
LOCATION
16p12.3
LOCUSID
51704
ALIAS
RAIG-2,RAIG2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51704
MIM: 605948
HGNC: 13308
Ensembl: ENSG00000167191

Variants:

dbSNP: 51704
ClinVar: 51704
TCGA: ENSG00000167191
COSMIC: GPRC5B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167191ENST00000300571Q9NZH0
ENSG00000167191ENST00000300571A0A024QYX2
ENSG00000167191ENST00000535671Q9NZH0
ENSG00000167191ENST00000562469H3BQV9
ENSG00000167191ENST00000564449H3BT47
ENSG00000167191ENST00000566822H3BN33
ENSG00000167191ENST00000568214H3BT93
ENSG00000167191ENST00000569479Q9NZH0
ENSG00000167191ENST00000569479A0A024QYX2
ENSG00000167191ENST00000569847Q9NZH0
ENSG00000167191ENST00000569847A0A024QYX2
ENSG00000167191ENST00000570142H3BSJ1

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
366827962023GPRC5B (G protein-coupled receptor class C group 5 member B) suppresses glucose starvation-induced apoptosis in head-and-neck squamous cell carcinoma.0
366827962023GPRC5B (G protein-coupled receptor class C group 5 member B) suppresses glucose starvation-induced apoptosis in head-and-neck squamous cell carcinoma.0
341000782021Identification of the GlialCAM interactome: the G protein-coupled receptors GPRC5B and GPR37L1 modulate megalencephalic leukoencephalopathy proteins.6
350469322021Multi-Omics Analysis for Transcriptional Regulation of Immune-Related Targets Using Epigenetic Data: A New Research Direction.3
341000782021Identification of the GlialCAM interactome: the G protein-coupled receptors GPRC5B and GPR37L1 modulate megalencephalic leukoencephalopathy proteins.6
350469322021Multi-Omics Analysis for Transcriptional Regulation of Immune-Related Targets Using Epigenetic Data: A New Research Direction.3
319413582020Orphan G Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling.11
319413582020Orphan G Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling.11
309477442019Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases.13
311047672019The orphan receptor GPRC5B modulates inflammatory and fibrotic pathways in cardiac fibroblasts and mice hearts.4
312852842019GPRC5b Modulates Inflammatory Response in Glomerular Diseases via NF-κB Pathway.8
309477442019Shared genetic underpinnings of childhood obesity and adult cardiometabolic diseases.13
311047672019The orphan receptor GPRC5B modulates inflammatory and fibrotic pathways in cardiac fibroblasts and mice hearts.4
312852842019GPRC5b Modulates Inflammatory Response in Glomerular Diseases via NF-κB Pathway.8
300868842018Caveolin-1 prevents palmitate-induced NF-κB signaling by inhibiting GPRC5B-phosphorylation.8

Citation

Dessen P

GPRC5B (G protein-coupled receptor class C group 5 member B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64017/js/lib/tumors-explorer/