HIGD2A (HIG1 hypoxia inducible domain family member 2A)

2014-11-01  

Identity

HGNC
HIGD2A
LOCATION
5q35.2
LOCUSID
192286
ALIAS
RCF1b
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 192286
HGNC: 28311
Ensembl: ENSG00000146066

Variants:

dbSNP: 192286
ClinVar: 192286
TCGA: ENSG00000146066
COSMIC: HIGD2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146066ENST00000274787Q9BW72
ENSG00000146066ENST00000274787A0A024R7Q3

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
350088152021Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress.1
350088152021Dynamic Distribution of HIG2A between the Mitochondria and the Nucleus in Response to Hypoxia and Oxidative Stress.1
320854612020Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology.7
323172972020HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.22
320854612020Biosystem Analysis of the Hypoxia Inducible Domain Family Member 2A: Implications in Cancer Biology.7
323172972020HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV.22
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

HIGD2A (HIG1 hypoxia inducible domain family member 2A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64269