KRT77 (keratin 77)

2014-11-01  

Identity

HGNC
KRT77
LOCATION
12q13.13
LOCUSID
374454
ALIAS
K1B,KRT1B

Other Information

Locus ID:

NCBI: 374454
MIM: 611158
HGNC: 20411
Ensembl: ENSG00000189182

Variants:

dbSNP: 374454
ClinVar: 374454
TCGA: ENSG00000189182
COSMIC: KRT77

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189182ENST00000341809Q7Z794
ENSG00000189182ENST00000553168F8VS61

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
329278882020Molecular Modeling of Pathogenic Mutations in the Keratin 1B Domain.3
329278882020Molecular Modeling of Pathogenic Mutations in the Keratin 1B Domain.3
161177822005Characterization of a novel human type II epithelial keratin K1b, specifically expressed in eccrine sweat glands.19
161177822005Characterization of a novel human type II epithelial keratin K1b, specifically expressed in eccrine sweat glands.19

Citation

Dessen P

KRT77 (keratin 77)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65041