ANTXR1 (ANTXR cell adhesion molecule 1)

2003-06-01  

Identity

HGNC
ANTXR1
LOCATION
2p13.3
LOCUSID
84168
ALIAS
ATR,GAPO,TEM8
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84168
MIM: 606410
HGNC: 21014
Ensembl: ENSG00000169604

Variants:

dbSNP: 84168
ClinVar: 84168
TCGA: ENSG00000169604
COSMIC: ANTXR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169604ENST00000303714Q9H6X2
ENSG00000169604ENST00000409349Q9H6X2
ENSG00000169604ENST00000409829Q9H6X2
ENSG00000169604ENST00000482235H0YC24

Expression (GTEx)

0
50
100
150
200
250
300
350
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
Uptake and actions of bacterial toxinsREACTOMER-HSA-5339562
Uptake and function of anthrax toxinsREACTOMER-HSA-5210891

References

Pubmed IDYearTitleCitations
386537892024ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder.0
386537892024ANTXR1 deficiency promotes fibroblast senescence: implications for GAPO syndrome as a progeroid disorder.0
367488302023Two siblings with GAPO syndrome: Ophthalmic presentation and histopathologic findings.1
379743572023Depleting ANTXR1 suppresses glioma growth via deactivating PI3K/AKT pathway.0
367488302023Two siblings with GAPO syndrome: Ophthalmic presentation and histopathologic findings.1
379743572023Depleting ANTXR1 suppresses glioma growth via deactivating PI3K/AKT pathway.0
359422092022Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/β-Catenin Signaling Pathway.0
360653342022ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt/β-Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell.0
359422092022Transmembrane Protein ANTXR1 Regulates γ-Globin Expression by Targeting the Wnt/β-Catenin Signaling Pathway.0
360653342022ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt/β-Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell.0
337227772021Circular RNA circAFF2 accelerates gastric cancer development by activating miR-6894-5p and regulating ANTXR 1 expression.8
339247742021N-Linked Glycosylation on Anthrax Toxin Receptor 1 Is Essential for Seneca Valley Virus Infection.5
341651552021Targeted silencing of TEM8 suppresses non‑small cell lung cancer tumor growth via the ERK/Bcl‑2 signaling pathway.3
342852102021TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer.17
342891662021Overexpression of tumor endothelial marker 8 protein predicts poor prognosis in angiosarcoma.2

Citation

Dessen P

ANTXR1 (ANTXR cell adhesion molecule 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/652/gene-explorer/haematological-explorer/js/_common.js