LHX8 (LIM homeobox 8)

2014-11-01  

Identity

HGNC
LHX8
LOCATION
1p31.1
LOCUSID
431707
ALIAS
LHX7

Other Information

Locus ID:

NCBI: 431707
MIM: 604425
HGNC: 28838
Ensembl: ENSG00000162624

Variants:

dbSNP: 431707
ClinVar: 431707
TCGA: ENSG00000162624
COSMIC: LHX8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162624ENST00000294638Q68G74
ENSG00000162624ENST00000356261Q68G74

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
387035832024LIM homeobox 8 reduced apoptosis and promoted periodontal tissue regeneration function of dental pulp stem cells.0
387035832024LIM homeobox 8 reduced apoptosis and promoted periodontal tissue regeneration function of dental pulp stem cells.0
363668272023Validation of ASCL1 and LHX8 Methylation Analysis as Primary Cervical Cancer Screening Strategy in South African Women with Human Immunodeficiency Virus.1
366020252023Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8.0
363668272023Validation of ASCL1 and LHX8 Methylation Analysis as Primary Cervical Cancer Screening Strategy in South African Women with Human Immunodeficiency Virus.1
366020252023Single-cell profiling of lncRNAs in human germ cells and molecular analysis reveals transcriptional regulation of LNC1845 on LHX8.0
351522242022Posttreatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3.1
360292992022Heterozygous loss-of-function variants in LHX8 cause female infertility characterized by oocyte maturation arrest.4
351522242022Posttreatment monitoring by ASCL1/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2/3.1
360292992022Heterozygous loss-of-function variants in LHX8 cause female infertility characterized by oocyte maturation arrest.4
243164042014Upregulation of Lhx8 increase VAChT expression and ACh release in neuronal cell line SHSY5Y.4
243164042014Upregulation of Lhx8 increase VAChT expression and ACh release in neuronal cell line SHSY5Y.4
224356492012Evaluation of the LIM homeobox genes LHX6 and LHX8 as candidates for Tourette syndrome.6
224356492012Evaluation of the LIM homeobox genes LHX6 and LHX8 as candidates for Tourette syndrome.6
211435302011Comparative study of LHX8 expression between odontoma and dental tissue-derived stem cells.5

Citation

Dessen P

LHX8 (LIM homeobox 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65257