LILRA6 (leukocyte immunoglobulin like receptor A6)

2014-11-01  

Identity

HGNC
LILRA6
LOCATION
19q13.42
LOCUSID
79168
ALIAS
CD85b,ILT-8,ILT5,ILT8,LILRB3,LILRB6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79168
HGNC: 15495
Ensembl: ENSG00000244482

Variants:

dbSNP: 79168
ClinVar: 79168
TCGA: ENSG00000244482
COSMIC: LILRA6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000244482ENST00000245621B5ME96
ENSG00000244482ENST00000396365Q6PI73
ENSG00000244482ENST00000396365U5XH19
ENSG00000244482ENST00000430421Q6PI73

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
364490532023Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.3
364490532023Distinct frequency patterns of LILRB3 and LILRA6 allelic variants in Europeans.3
335268152021Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.3
335268152021Characterization of LILRB3 and LILRA6 allelic variants in the Japanese population.3
273338112016LILRA6 copy number variation correlates with susceptibility to atopic dermatitis.4
273338112016LILRA6 copy number variation correlates with susceptibility to atopic dermatitis.4
240969702014Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.22
240969702014Diversity of the human LILRB3/A6 locus encoding a myeloid inhibitory and activating receptor pair.22
203313782010Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.30
203313782010Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.30
196175792009Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.21
196175792009Allogeneic disparities in immunoglobulin-like transcript 5 induce potent antibody responses in hematopoietic stem cell transplant recipients.21

Citation

Dessen P

LILRA6 (leukocyte immunoglobulin like receptor A6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/65264