ANXA5 (annexin A5)

2003-08-01  

Identity

HGNC
ANXA5
LOCATION
4q27
LOCUSID
308
ALIAS
ANX5,ENX2,HEL-S-7,PP4,RPRGL3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 308
MIM: 131230
HGNC: 543
Ensembl: ENSG00000164111

Variants:

dbSNP: 308
ClinVar: 308
TCGA: ENSG00000164111
COSMIC: ANXA5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164111ENST00000296511P08758
ENSG00000164111ENST00000296511V9HWE0
ENSG00000164111ENST00000501272D6RBL5
ENSG00000164111ENST00000506395E9PHT9
ENSG00000164111ENST00000513728D6RCN3
ENSG00000164111ENST00000515017D6RBE9

Expression (GTEx)

0
500
1000
1500
2000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384741142024The Relevance, Predictability, and Utility of Annexin A5 for Human Physiopathology.2
388243862024ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular Carcinoma.0
384741142024The Relevance, Predictability, and Utility of Annexin A5 for Human Physiopathology.2
388243862024ANXA5: A Key Regulator of Immune Cell Infiltration in Hepatocellular Carcinoma.0
369580132023Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish.3
372728422023Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Cα (PKCα) and PKCη Expression, Thereby Promoting Viral Propagation.0
369580132023Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish.3
372728422023Hepatitis C Virus Disrupts Annexin 5-Mediated Occludin Integrity through Downregulation of Protein Kinase Cα (PKCα) and PKCη Expression, Thereby Promoting Viral Propagation.0
348781502022Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.0
352458572022Clinicopathological study and immunohistochemical analysis of expression of annexin A5 and apelin in human placentae of gestational diabetes mellitus.2
358999142022Association between ANXA5 haplotypes and the risk of recurrent pregnancy loss.2
359127322022Increased ANXA5 expression in stomach adenocarcinoma infers a poor prognosis and high level of immune infiltration.5
359403922022Annexin A5 as a targeting agent for cancer treatment.10
348781502022Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.0
352458572022Clinicopathological study and immunohistochemical analysis of expression of annexin A5 and apelin in human placentae of gestational diabetes mellitus.2

Citation

Dessen P

ANXA5 (annexin A5)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/656