APC2 (APC regulator of WNT signaling pathway 2)

2003-02-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
APCL
FUSION GENES

Other Information

Locus ID:

NCBI: 10297
MIM: 612034
HGNC: 24036
Ensembl: ENSG00000115266

Variants:

dbSNP: 10297
ClinVar: 10297
TCGA: ENSG00000115266
COSMIC: APC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115266ENST00000233607O95996
ENSG00000115266ENST00000238483B5MDS5
ENSG00000115266ENST00000535453O95996
ENSG00000115266ENST00000587149K7ERC5
ENSG00000115266ENST00000587869K7EN62
ENSG00000115266ENST00000590469A0A0C4DGQ0
ENSG00000115266ENST00000590877K7ELQ3

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Wnt signaling pathwayKEGGko04310
Regulation of actin cytoskeletonKEGGko04810
Colorectal cancerKEGGko05210
Endometrial cancerKEGGko05213
Basal cell carcinomaKEGGko05217
Wnt signaling pathwayKEGGhsa04310
Regulation of actin cytoskeletonKEGGhsa04810
Pathways in cancerKEGGhsa05200
Colorectal cancerKEGGhsa05210
Endometrial cancerKEGGhsa05213
Basal cell carcinomaKEGGhsa05217
HTLV-I infectionKEGGko05166
HTLV-I infectionKEGGhsa05166
Hippo signaling pathwayKEGGhsa04390
Hippo signaling pathwayKEGGko04390
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206
Signaling pathways regulating pluripotency of stem cellsKEGGhsa04550
Signaling pathways regulating pluripotency of stem cellsKEGGko04550
Breast cancerKEGGko05224
Breast cancerKEGGhsa05224

References

Pubmed IDYearTitleCitations
385230342024Reprint of: Recessive APC2 missense variants associated with epilepsies without neurodevelopmental disorders.0
385230342024Reprint of: Recessive APC2 missense variants associated with epilepsies without neurodevelopmental disorders.0
376573062023Recessive APC2 missense variants associated with epilepsies without neurodevelopmental disorders.1
376573062023Recessive APC2 missense variants associated with epilepsies without neurodevelopmental disorders.1
349272282022High miR-3648 expression and low APC2 expression are associated with shorter survival and tumor progression in NSCLC.1
349272282022High miR-3648 expression and low APC2 expression are associated with shorter survival and tumor progression in NSCLC.1
341551972021METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N(6)-methyladenosine-dependent YTHDF binding.66
346370962021What are the roles of global DNA and APC 2 gene promotor hypermethylation in multiple myeloma?1
341551972021METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N(6)-methyladenosine-dependent YTHDF binding.66
346370962021What are the roles of global DNA and APC 2 gene promotor hypermethylation in multiple myeloma?1
327256322020Whole-exome sequencing in adult patients with developmental and epileptic encephalopathy: It is never too late.14
327256322020Whole-exome sequencing in adult patients with developmental and epileptic encephalopathy: It is never too late.14
311099672019Hsa_circ_0009361 acts as the sponge of miR-582 to suppress colorectal cancer progression by regulating APC2 expression.63
311962562019miR-3648 Promotes Prostate Cancer Cell Proliferation by Inhibiting Adenomatous Polyposis Coli 2.9
312062082019circ-PKD2 inhibits carcinogenesis via the miR-204-3p/APC2 axis in oral squamous cell carcinoma.29

Citation

Dessen P

APC2 (APC regulator of WNT signaling pathway 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/666/haematological-explorer/js/lib/tumors-explorer/