Identity
HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
AARE,ACPH,APH,D3F15S2,D3S48E,DNF15S2,OPH
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 327
MIM: 102645
HGNC: 586
Ensembl: ENSG00000164062
Variants:
dbSNP: 327
ClinVar: 327
TCGA: ENSG00000164062
COSMIC: APEH
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33471263 | 2021 | Selective inhibition of acylpeptide hydrolase in SAOS-2 osteosarcoma cells: is this enzyme a viable anticancer target? | 3 |
| 33753553 | 2021 | Deubiquitinase UCHL1 Maintains Protein Homeostasis through the PSMA7-APEH-Proteasome Axis in High-grade Serous Ovarian Carcinoma. | 10 |
| 33471263 | 2021 | Selective inhibition of acylpeptide hydrolase in SAOS-2 osteosarcoma cells: is this enzyme a viable anticancer target? | 3 |
| 33753553 | 2021 | Deubiquitinase UCHL1 Maintains Protein Homeostasis through the PSMA7-APEH-Proteasome Axis in High-grade Serous Ovarian Carcinoma. | 10 |
| 31266814 | 2019 | Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function. | 13 |
| 31266814 | 2019 | Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function. | 13 |
| 28866241 | 2017 | Acylpeptide hydrolase is a component of the cellular response to DNA damage. | 11 |
| 28866241 | 2017 | Acylpeptide hydrolase is a component of the cellular response to DNA damage. | 11 |
| 27406852 | 2016 | Influence of acylpeptide hydrolase polymorphisms on valproic acid level in Chinese epilepsy patients. | 7 |
| 27406852 | 2016 | Influence of acylpeptide hydrolase polymorphisms on valproic acid level in Chinese epilepsy patients. | 7 |
| 21931648 | 2011 | Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review. | 12 |
| 21931648 | 2011 | Genetic evidence supporting the association of protease and protease inhibitor genes with inflammatory bowel disease: a systematic review. | 12 |
| 20307617 | 2010 | Association analysis of 3p21 with Crohn's disease in a New Zealand population. | 4 |
| 20529763 | 2010 | Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE. | 8 |
| 20307617 | 2010 | Association analysis of 3p21 with Crohn's disease in a New Zealand population. | 4 |
Citation
Dessen P
APEH (acylaminoacyl-peptide hydrolase)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/668/apeh
