MPP7 (membrane palmitoylated protein 7)

2014-11-01 Affiliation

Identity

HGNC

MPP7

LOCATION

10p12.1

LOCUSID

143098

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 143098
MIM: 610973
HGNC: 26542
Ensembl: ENSG00000150054

Variants:

dbSNP: 143098
ClinVar: 143098
TCGA: ENSG00000150054
COSMIC: MPP7

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000150054	ENST00000337532	Q5T2T1
ENSG00000150054	ENST00000375719	Q5T2T1
ENSG00000150054	ENST00000375732	Q5T2T1
ENSG00000150054	ENST00000441595	U5GXS2
ENSG00000150054	ENST00000496637	S4R337

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
37194388	2023	A common variant SNP rs1937810 in the MPP7 gene contributes to the susceptibility of breast cancer in the Chinese Han population.	1
37194388	2023	A common variant SNP rs1937810 in the MPP7 gene contributes to the susceptibility of breast cancer in the Chinese Han population.	1
33377561	2021	MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling.	7
33377561	2021	MPP7 promotes the migration and invasion of breast cancer cells via EGFR/AKT signaling.	7
31772230	2019	Relationship of common variants in MPP7, TIMP2 and CASP8 genes with the risk of chronic achilles tendinopathy.	4
31772230	2019	Relationship of common variants in MPP7, TIMP2 and CASP8 genes with the risk of chronic achilles tendinopathy.	4
27001270	2016	Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma.	11
27001270	2016	Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma.	11
22171069	2012	Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specific bone mineral density.	17
22171069	2012	Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specific bone mineral density.	17
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20702775	2010	Structural basis for tandem L27 domain-mediated polymerization.	8
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20702775	2010	Structural basis for tandem L27 domain-mediated polymerization.	8
17237226	2007	The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions.	37

Citation

Dessen P

MPP7 (membrane palmitoylated protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70394