MRGPRX3 (MAS related GPR family member X3)

2014-11-01 Affiliation

Identity

HGNC

MRGPRX3

LOCATION

11p15.1

LOCUSID

117195

ALIAS

GPCR,MRGX3,SNSR1,SNSR2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 117195
MIM: 607229
HGNC: 17980
Ensembl: ENSG00000179826

Variants:

dbSNP: 117195
ClinVar: 117195
TCGA: ENSG00000179826
COSMIC: MRGPRX3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000179826	ENST00000396275	Q96LB0
ENSG00000179826	ENST00000531264	E9PPY5
ENSG00000179826	ENST00000621697	Q96LB0

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
34552215	2022	GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.	0
34552215	2022	GPCR-mediated EGFR transactivation ameliorates skin toxicities induced by afatinib.	0
29408502	2018	GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro.	15
29408502	2018	GPR182 is a novel marker for sinusoidal endothelial differentiation with distinct GPCR signaling activity in vitro.	15
28189739	2017	Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease.	23
28189739	2017	Potential of GPCRs to modulate MAPK and mTOR pathways in Alzheimer's disease.	23
15809047	2005	Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype.	0
15809047	2005	Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype.	0

Citation

Dessen P

MRGPRX3 (MAS related GPR family member X3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70416