MTFP1 (mitochondrial fission process 1)

2014-11-01  

Identity

HGNC
MTFP1
LOCATION
22q12.2
LOCUSID
51537
ALIAS
HSPC242,MTP18

Other Information

Locus ID:

NCBI: 51537
MIM: 610235
HGNC: 26945
Ensembl: ENSG00000242114

Variants:

dbSNP: 51537
ClinVar: 51537
TCGA: ENSG00000242114
COSMIC: MTFP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000242114ENST00000266263Q9UDX5
ENSG00000242114ENST00000266263A0A024R1E4
ENSG00000242114ENST00000355143Q9UDX5
ENSG00000242114ENST00000407550B5MC22
ENSG00000242114ENST00000412752F8WEN7
ENSG00000242114ENST00000629597F8WEN7

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
380422182024Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models.1
380422182024Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models.1
363802602023MiR-125b-5p Targets MTFP1 to Inhibit Cell Proliferation, Migration, and Invasion and Facilitate Cell Apoptosis in Endometrial Carcinoma.2
373137422023The inner mitochondrial membrane fission protein MTP18 serves as a mitophagy receptor to prevent apoptosis in oral cancer.2
363802602023MiR-125b-5p Targets MTFP1 to Inhibit Cell Proliferation, Migration, and Invasion and Facilitate Cell Apoptosis in Endometrial Carcinoma.2
373137422023The inner mitochondrial membrane fission protein MTP18 serves as a mitophagy receptor to prevent apoptosis in oral cancer.2
318142132020MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.4
318142132020MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production.4
303257402018MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury.62
303257402018MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury.62
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
195787962009Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.8
198785692009Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.33
195787962009Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.8

Citation

Dessen P

MTFP1 (mitochondrial fission process 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70541