MXRA8 (matrix remodeling associated 8)

2014-11-01  

Identity

HGNC
MXRA8
LOCATION
1p36.33
LOCUSID
54587
ALIAS
ASP3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54587
MIM: 617293
HGNC: 7542
Ensembl: ENSG00000162576

Variants:

dbSNP: 54587
ClinVar: 54587
TCGA: ENSG00000162576
COSMIC: MXRA8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162576ENST00000309212Q9BRK3
ENSG00000162576ENST00000342753Q9BRK3
ENSG00000162576ENST00000445648Q9BRK3
ENSG00000162576ENST00000477278Q9BRK3

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
384415502024Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8.0
384415502024Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8.0
377620322023Loss of MXRA8 Delays Mammary Tumor Development and Impairs Metastasis.1
377620322023Loss of MXRA8 Delays Mammary Tumor Development and Impairs Metastasis.1
354564972022Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo.5
354564972022Elevated Expression of miR-200c/141 in MDA-MB-231 Cells Suppresses MXRA8 Levels and Impairs Breast Cancer Growth and Metastasis In Vivo.5
310800612019Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.76
310800632019Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.56
310800612019Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor.76
310800632019Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein.56
233862762013DICAM inhibits angiogenesis via suppression of AKT and p38 MAP kinase signalling.19
233862762013DICAM inhibits angiogenesis via suppression of AKT and p38 MAP kinase signalling.19
215555182011The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.95
215555182011The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.95
146034612003Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet.20

Citation

Dessen P

MXRA8 (matrix remodeling associated 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70594/cancer-prone-explorer/gene-explorer/css/template-nav.css