MYH7B (myosin heavy chain 7B)

2014-11-01  

Identity

HGNC
MYH7B
LOCATION
20q11.22
LOCUSID
57644
ALIAS
MHC14,MYH14
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57644
MIM: 609928
HGNC: 15906
Ensembl: ENSG00000078814

Variants:

dbSNP: 57644
ClinVar: 57644
TCGA: ENSG00000078814
COSMIC: MYH7B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078814ENST00000262873A7E2Y1
ENSG00000078814ENST00000433934Q5JW47
ENSG00000078814ENST00000435272Q5JW49
ENSG00000078814ENST00000446156Q5JW48
ENSG00000078814ENST00000453028Q5JW46
ENSG00000078814ENST00000456649Q5JW45
ENSG00000078814ENST00000618182A0A087X0T3

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Tight junctionKEGGko04530
Tight junctionKEGGhsa04530
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Translocation of GLUT4 to the plasma membraneREACTOMER-HSA-1445148

References

Pubmed IDYearTitleCitations
363346272023Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles.10
369634942023Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b.1
363346272023Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles.10
369634942023Distinct effects of two hearing loss-associated mutations in the sarcomeric myosin MYH7b.1
338951322021Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart.10
338951322021Myosin 7b is a regulatory long noncoding RNA (lncMYH7b) in the human heart.10
276669692016Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex.31
276669692016Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex.31
238002892013Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy.20
238002892013Digenic mutational inheritance of the integrin alpha 7 and the myosin heavy chain 7B genes causes congenital myopathy with left ventricular non-compact cardiomyopathy.20
199486552010Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.67
201541442010Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping.72
202243052010Modest association of malignant melanoma with the rs910873 and rs1885120 markers on chromosome 20: a population-based study.1
205206192010Common genetic variants in pre-microRNAs and risk of gallbladder cancer in North Indian population.44
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15

Citation

Dessen P

MYH7B (myosin heavy chain 7B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70610/img/gene-fusions/js/lib/popper.js