NKIRAS2 (NFKB inhibitor interacting Ras like 2)

2014-11-01  

Identity

HGNC
NKIRAS2
LOCATION
17q21.2
LOCUSID
28511
ALIAS
KBRAS2,kappaB-Ras2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 28511
MIM: 604497
HGNC: 17898
Ensembl: ENSG00000168256

Variants:

dbSNP: 28511
ClinVar: 28511
TCGA: ENSG00000168256
COSMIC: NKIRAS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168256ENST00000307641Q9NYR9
ENSG00000168256ENST00000307641A0A024R1Z4
ENSG00000168256ENST00000316082H7BXP1
ENSG00000168256ENST00000393880Q9NYR9
ENSG00000168256ENST00000393880A0A024R1Z4
ENSG00000168256ENST00000393881Q9NYR9
ENSG00000168256ENST00000393881A0A024R1Z4
ENSG00000168256ENST00000393885Q9NYR9
ENSG00000168256ENST00000393885A0A024R1Z4
ENSG00000168256ENST00000449471Q9NYR9
ENSG00000168256ENST00000462043A0A0A0MTA0
ENSG00000168256ENST00000479407Q9NYR9
ENSG00000168256ENST00000485789K7ELL8
ENSG00000168256ENST00000491638K7EKE9
ENSG00000168256ENST00000585955K7ER26
ENSG00000168256ENST00000587337K7ERG2

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
346672242021K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors.0
346672242021K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors.0
249010502014miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas.39
249010502014miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas.39
206391962010KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.13
206391962010KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.13
184344482009Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.13
184344482009Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.13

Citation

Dessen P

NKIRAS2 (NFKB inhibitor interacting Ras like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70852