NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor)

2014-11-01  

Identity

HGNC
NSMF
LOCATION
9q34.3
LOCUSID
26012
ALIAS
HH9,NELF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 26012
MIM: 608137
HGNC: 29843
Ensembl: ENSG00000165802

Variants:

dbSNP: 26012
ClinVar: 26012
TCGA: ENSG00000165802
COSMIC: NSMF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165802ENST00000265663Q6X4W1
ENSG00000165802ENST00000371472Q6X4W1
ENSG00000165802ENST00000371473Q6X4W1
ENSG00000165802ENST00000371474Q6X4W1
ENSG00000165802ENST00000371475Q6X4W1
ENSG00000165802ENST00000437259Q6X4W1
ENSG00000165802ENST00000482448A0A1B0GUJ1

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381828972024NELF and PAF1C complexes are core transcriptional machineries controlling colon cancer stemness.0
381828972024NELF and PAF1C complexes are core transcriptional machineries controlling colon cancer stemness.0
339638722021NSMF promotes the replication stress-induced DNA damage response for genome maintenance.6
339638722021NSMF promotes the replication stress-induced DNA damage response for genome maintenance.6
290508622018JAK/STAT signaling pathway gene expression is reduced following Nelf knockdown in GnRH neurons.6
290508622018JAK/STAT signaling pathway gene expression is reduced following Nelf knockdown in GnRH neurons.6
243163762014Differential expression of nasal embryonic LHRH factor (NELF) variants in immortalized GnRH neuronal cell lines.2
243163762014Differential expression of nasal embryonic LHRH factor (NELF) variants in immortalized GnRH neuronal cell lines.2
238844112013Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription.45
238844112013Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription.45
213003402011Nasal embryonic LHRH factor (NELF) mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome.28
213003402011Nasal embryonic LHRH factor (NELF) mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome.28
194898742010Screening of autosomal gene deletions in patients with hypogonadotropic hypogonadism using multiplex ligation-dependent probe amplification: detection of a hemizygosis for the fibroblast growth factor receptor 1.14
200259342010NELF is a nuclear protein involved in hypothalamic GnRH neuronal migration.10
194898742010Screening of autosomal gene deletions in patients with hypogonadotropic hypogonadism using multiplex ligation-dependent probe amplification: detection of a hemizygosis for the fibroblast growth factor receptor 1.14

Citation

Dessen P

NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70988