NUBP1 (nucleotide binding protein 1)

2014-11-01  

Identity

HGNC
NUBP1
LOCATION
16p13.13
LOCUSID
4682
ALIAS
CIAO5,NBP,NBP1,NBP35
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4682
MIM: 600280
HGNC: 8041
Ensembl: ENSG00000103274

Variants:

dbSNP: 4682
ClinVar: 4682
TCGA: ENSG00000103274
COSMIC: NUBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103274ENST00000283027P53384
ENSG00000103274ENST00000433392P53384
ENSG00000103274ENST00000571175I3L3A0
ENSG00000103274ENST00000574334I3L531
ENSG00000103274ENST00000574691I3L518

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Cytosolic iron-sulfur cluster assemblyREACTOMER-HSA-2564830

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369167542023Unraveling the mechanism of [4Fe-4S] cluster assembly on the N-terminal cluster binding site of NUBP1.2
369167542023Unraveling the mechanism of [4Fe-4S] cluster assembly on the N-terminal cluster binding site of NUBP1.2
324296692020GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron-Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1.9
324296692020GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron-Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1.9
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.11
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.17
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.11
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.17
185738742008Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis.44
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.36
185738742008Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis.44
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.36

Citation

Dessen P

NUBP1 (nucleotide binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71009/gene-fusions/gene-explorer/deep-insight-explorer/