OPALIN (oligodendrocytic myelin paranodal and inner loop protein)

2014-11-01  

Identity

HGNC
OPALIN
LOCATION
10q24.1
LOCUSID
93377
ALIAS
HTMP10,TMEM10,TMP10

Other Information

Locus ID:

NCBI: 93377
MIM: 617200
HGNC: 20707
Ensembl: ENSG00000197430

Variants:

dbSNP: 93377
ClinVar: 93377
TCGA: ENSG00000197430
COSMIC: OPALIN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197430ENST00000371172Q96PE5
ENSG00000197430ENST00000393870A0A0A0MS47
ENSG00000197430ENST00000393871Q96PE5
ENSG00000197430ENST00000419479Q96PE5
ENSG00000197430ENST00000536387A0A0A0MTN4
ENSG00000197430ENST00000611913Q96PE5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
308376462019TMEM10 Promotes Oligodendrocyte Differentiation and is Expressed by Oligodendrocytes in Human Remyelinating Multiple Sclerosis Plaques.21
308376462019TMEM10 Promotes Oligodendrocyte Differentiation and is Expressed by Oligodendrocytes in Human Remyelinating Multiple Sclerosis Plaques.21
184904492008Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane.25
184904492008Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane.25

Citation

Dessen P

OPALIN (oligodendrocytic myelin paranodal and inner loop protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71126/gene-explorer/deep-insight-explorer/