ASTN2 (astrotactin 2)

2003-05-01  

Identity

HGNC
ASTN2
LOCATION
9q33.1
LOCUSID
23245
ALIAS
bA67K19.1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23245
MIM: 612856
HGNC: 17021
Ensembl: ENSG00000148219

Variants:

dbSNP: 23245
ClinVar: 23245
TCGA: ENSG00000148219
COSMIC: ASTN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148219ENST00000288520O75129
ENSG00000148219ENST00000313400O75129
ENSG00000148219ENST00000341734O75129
ENSG00000148219ENST00000358637X6R5P2
ENSG00000148219ENST00000361209O75129
ENSG00000148219ENST00000361477B7ZKP5
ENSG00000148219ENST00000373986H0Y3A8
ENSG00000148219ENST00000417725H7C3I6

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
333883712021Chimeric RNA ASTN2-PAPPA(as) aggravates tumor progression and metastasis in human esophageal cancer.17
334764602021Effects of rs958804 and rs7858836 single-nucleotide polymorphisms of the ASTN2 gene on pain-related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy.5
344120802021Rare copy number variants in ASTN2 gene in patients with neurodevelopmental disorders.6
344403682021Genetic Variation in the ASTN2 Locus in Cardiovascular, Metabolic and Psychiatric Traits: Evidence for Pleiotropy Rather Than Shared Biology.3
333883712021Chimeric RNA ASTN2-PAPPA(as) aggravates tumor progression and metastasis in human esophageal cancer.17
334764602021Effects of rs958804 and rs7858836 single-nucleotide polymorphisms of the ASTN2 gene on pain-related phenotypes in patients who underwent laparoscopic colectomy and mandibular sagittal split ramus osteotomy.5
344120802021Rare copy number variants in ASTN2 gene in patients with neurodevelopmental disorders.6
344403682021Genetic Variation in the ASTN2 Locus in Cardiovascular, Metabolic and Psychiatric Traits: Evidence for Pleiotropy Rather Than Shared Biology.3
302421342018ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.29
302421342018ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.29
280587302017Multilocus analysis reveals three candidate genes for Chinese migraine susceptibility.6
280587302017Multilocus analysis reveals three candidate genes for Chinese migraine susceptibility.6
271384302016The role of ASTN2 variants in childhood and adult ADHD, comorbid disorders and associated personality traits.4
272496422016Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development.16
271384302016The role of ASTN2 variants in childhood and adult ADHD, comorbid disorders and associated personality traits.4

Citation

Dessen P

ASTN2 (astrotactin 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/717/js/lib/gene-explorer/meetings/