PDC (phosducin)

2014-11-01 Affiliation

Identity

HGNC

PDC

LOCATION

1q31.1

LOCUSID

5132

ALIAS

MEKA,PHD,PhLOP,PhLP

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 5132
MIM: 171490
HGNC: 8759
Ensembl: ENSG00000116703

Variants:

dbSNP: 5132
ClinVar: 5132
TCGA: ENSG00000116703
COSMIC: PDC

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000116703	ENST00000391997	P20941
ENSG00000116703	ENST00000497198	P20941
ENSG00000116703	ENST00000497198	A0A024R982

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25153685	2015	Phosducin regulates secretory activity in TT line of thyroid parafollicular C cells.	0
25153685	2015	Phosducin regulates secretory activity in TT line of thyroid parafollicular C cells.	0
22365573	2013	Phosducin rs12402521 polymorphism predicts development of hypertension in young subjects with overweight or obesity.	1
22365573	2013	Phosducin rs12402521 polymorphism predicts development of hypertension in young subjects with overweight or obesity.	1
21191291	2011	The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation.	2
21191291	2011	The identification of phosducin as a novel candidate gene for hypertension and its role in sympathetic activation.	2
20804785	2010	Phosducin and monomeric β-actin have common epitope recognized by anti-phosducin antibodies.	1
20804785	2010	Phosducin and monomeric β-actin have common epitope recognized by anti-phosducin antibodies.	1
19959875	2009	Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.	16
19959875	2009	Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.	16
16421094	2006	SUMO-1 controls the protein stability and the biological function of phosducin.	35
16421094	2006	SUMO-1 controls the protein stability and the biological function of phosducin.	35
14758335	2004	Mutation screening of the phosducin gene PDC in patients with retinitis pigmentosa and allied diseases.	3
14758335	2004	Mutation screening of the phosducin gene PDC in patients with retinitis pigmentosa and allied diseases.	3
14758335	2004	Mutation screening of the phosducin gene PDC in patients with retinitis pigmentosa and allied diseases.	3

Citation

Dessen P

PDC (phosducin)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71781