PRB2 (proline rich protein BstNI subfamily 2)

2014-11-01 Affiliation

Identity

HGNC

PRB2

LOCATION

12p13.2

LOCUSID

653247

ALIAS

IB-9,PRPPRB1,Ps,cP7

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 653247
MIM: 168810
HGNC: 9338
Ensembl: ENSG00000121335

Variants:

dbSNP: 653247
ClinVar: 653247
TCGA: ENSG00000121335
COSMIC: PRB2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000121335	ENST00000389362	P02812
ENSG00000121335	ENST00000565533	H3BR58

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Salivary secretion	KEGG	ko04970
Salivary secretion	KEGG	hsa04970

References

Pubmed ID	Year	Title	Citations
25205458	2015	pRb2/p130 localizes to the cytoplasm in diffuse gastric cancer.	7
25205458	2015	pRb2/p130 localizes to the cytoplasm in diffuse gastric cancer.	7
15923424	2005	The regulation of ER-alpha transcription by pRb2/p130 in breast cancer.	3
15923424	2005	The regulation of ER-alpha transcription by pRb2/p130 in breast cancer.	3
15077161	2004	Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.	31
15077161	2004	Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.	31

Citation

Dessen P

PRB2 (proline rich protein BstNI subfamily 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72189