PRRG4 (proline rich and Gla domain 4)

2014-11-01  

Identity

HGNC
PRRG4
LOCATION
11p13
LOCUSID
79056
ALIAS
PRGP4,TMG4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79056
MIM: 611690
HGNC: 30799
Ensembl: ENSG00000135378

Variants:

dbSNP: 79056
ClinVar: 79056
TCGA: ENSG00000135378
COSMIC: PRRG4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135378ENST00000257836Q9BZD6
ENSG00000135378ENST00000257836A0A0S2Z5N9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
330374082020PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1.15
330374082020PRRG4 promotes breast cancer metastasis through the recruitment of NEDD4 and downregulation of Robo1.15
288590782017The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene.27
288590782017The WAGR syndrome gene PRRG4 is a functional homologue of the commissureless axon guidance gene.27
243572512014Narrowing of the responsible region for severe developmental delay and autistic behaviors in WAGR syndrome down to 1.6 Mb including PAX6, WT1, and PRRG4.15
243572512014Narrowing of the responsible region for severe developmental delay and autistic behaviors in WAGR syndrome down to 1.6 Mb including PAX6, WT1, and PRRG4.15
238739302013Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.10
238739302013Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2.10

Citation

Dessen P

PRRG4 (proline rich and Gla domain 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72295/css/favicon/cancer-prone-explorer/