RBM45 (RNA binding motif protein 45)

2014-11-01 Affiliation

Identity

HGNC

RBM45

LOCATION

2q31.2

LOCUSID

129831

ALIAS

DRB1,RB-1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 129831
MIM: 608888
HGNC: 24468
Ensembl: ENSG00000155636

Variants:

dbSNP: 129831
ClinVar: 129831
TCGA: ENSG00000155636
COSMIC: RBM45

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000155636	ENST00000286070	Q8IUH3
ENSG00000155636	ENST00000424099	H7BZE0
ENSG00000155636	ENST00000455903	H7C476
ENSG00000155636	ENST00000616198	Q8IUH3

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38040804	2024	RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.	1
38040804	2024	RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.	1
36435031	2023	Molecular basis of ssDNA recognition by RBM45 protein of neurodegenerative disease from multiple molecular dynamics simulations and energy predictions.	0
36435031	2023	Molecular basis of ssDNA recognition by RBM45 protein of neurodegenerative disease from multiple molecular dynamics simulations and energy predictions.	0
33577684	2021	Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.	4
34118419	2021	Family-based exome sequencing identifies RBM45 as a possible candidate gene for frontotemporal dementia and amyotrophic lateral sclerosis.	1
33577684	2021	Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.	4
34118419	2021	Family-based exome sequencing identifies RBM45 as a possible candidate gene for frontotemporal dementia and amyotrophic lateral sclerosis.	1
32156816	2020	RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers.	12
32156816	2020	RNA Binding Motif Protein RBM45 Regulates Expression of the 11-Kilodalton Protein of Parvovirus B19 through Binding to Novel Intron Splicing Enhancers.	12
29140459	2017	RBM45 competes with HDAC1 for binding to FUS in response to DNA damage.	15
29140459	2017	RBM45 competes with HDAC1 for binding to FUS in response to DNA damage.	15
26979993	2016	Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.	29
27226551	2016	Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.	11
26979993	2016	Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein-protein interaction network.	29

Citation

Dessen P

RBM45 (RNA binding motif protein 45)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72528