SAR1A (secretion associated Ras related GTPase 1A)

2014-11-01  

Identity

HGNC
LOCATION
10q22.1
LOCUSID
ALIAS
SAR1,SARA1,Sara,masra2
FUSION GENES

Other Information

Locus ID:

NCBI: 56681
MIM: 607691
HGNC: 10534
Ensembl: ENSG00000079332

Variants:

dbSNP: 56681
ClinVar: 56681
TCGA: ENSG00000079332
COSMIC: SAR1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000079332ENST00000373236Q5SQT8
ENSG00000079332ENST00000373238Q9NR31
ENSG00000079332ENST00000373238Q5SQT9
ENSG00000079332ENST00000373239X1WI22
ENSG00000079332ENST00000373241Q9NR31
ENSG00000079332ENST00000373241Q5SQT9
ENSG00000079332ENST00000373242Q9NR31
ENSG00000079332ENST00000373242Q5SQT9
ENSG00000079332ENST00000431664Q9NR31
ENSG00000079332ENST00000431664Q5SQT9
ENSG00000079332ENST00000452767H0Y5E8

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
COPII complexKEGGhsa_M00404
LegionellosisKEGGko05134
LegionellosisKEGGhsa05134
COPII complexKEGGM00404

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
386877992024Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.1
386877992024Functional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.1
360479712022SAR1A regulates the RhoA/YAP and autophagy signaling pathways to influence osteosarcoma invasion and metastasis.5
360479712022SAR1A regulates the RhoA/YAP and autophagy signaling pathways to influence osteosarcoma invasion and metastasis.5
323580662020Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly.13
323580662020Small sequence variations between two mammalian paralogs of the small GTPase SAR1 underlie functional differences in coat protein complex II assembly.13
304851592019Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes.9
304851592019Fatty-acid binding protein 5 modulates the SAR1 GTPase cycle and enhances budding of large COPII cargoes.9
297185412018Differential cell surface recruitment of the superoxide-producing NADPH oxidases Nox1, Nox2 and Nox5: The role of the small GTPase Sar1.5
300786782018Pull down assay for GTP-bound form of Sar1a reveals its activation during morphological differentiation.5
302516872018Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na(v)1.5.10
297185412018Differential cell surface recruitment of the superoxide-producing NADPH oxidases Nox1, Nox2 and Nox5: The role of the small GTPase Sar1.5
300786782018Pull down assay for GTP-bound form of Sar1a reveals its activation during morphological differentiation.5
302516872018Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Na(v)1.5.10
284993942017SAR1a promoter polymorphisms are not associated with fetal hemoglobin in patients with sickle cell disease from Cameroon.2

Citation

Dessen P

SAR1A (secretion associated Ras related GTPase 1A)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72979/js/css/lib/dataTables.bootstrap.min.css