SLC32A1 (solute carrier family 32 member 1)

2014-11-01 Affiliation

Identity

HGNC

SLC32A1

LOCATION

20q11.23

LOCUSID

140679

ALIAS

VGAT,VIAAT

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 140679
MIM: 616440
HGNC: 11018
Ensembl: ENSG00000101438

Variants:

dbSNP: 140679
ClinVar: 140679
TCGA: ENSG00000101438
COSMIC: SLC32A1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000101438	ENST00000217420	Q9H598

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Synaptic vesicle cycle	KEGG	ko04721
Synaptic vesicle cycle	KEGG	hsa04721
GABAergic synapse	KEGG	ko04727
GABAergic synapse	KEGG	hsa04727
Retrograde endocannabinoid signaling	KEGG	hsa04723
Retrograde endocannabinoid signaling	KEGG	ko04723
Morphine addiction	KEGG	hsa05032
Morphine addiction	KEGG	ko05032
Nicotine addiction	KEGG	hsa05033
Nicotine addiction	KEGG	ko05033
Neuronal System	REACTOME	R-HSA-112316
Transmission across Chemical Synapses	REACTOME	R-HSA-112315
Neurotransmitter Release Cycle	REACTOME	R-HSA-112310
GABA synthesis, release, reuptake and degradation	REACTOME	R-HSA-888590
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
SLC-mediated transmembrane transport	REACTOME	R-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptides	REACTOME	R-HSA-425393

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34038384	2021	Association of SLC32A1 Missense Variants With Genetic Epilepsy With Febrile Seizures Plus.	6
34038384	2021	Association of SLC32A1 Missense Variants With Genetic Epilepsy With Febrile Seizures Plus.	6
22510271	2012	Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons.	10
22510271	2012	Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons.	10
21396926	2011	Expression of VGluT1 and VGAT mRNAs in human dorsolateral prefrontal cortex during development and in schizophrenia.	14
21396926	2011	Expression of VGluT1 and VGAT mRNAs in human dorsolateral prefrontal cortex during development and in schizophrenia.	14
19874574	2009	Genetical genomic determinants of alcohol consumption in rats and humans.	107
19874574	2009	Genetical genomic determinants of alcohol consumption in rats and humans.	107
17471287	2008	Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia.	262
17471287	2008	Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia.	262
12115694	2002	Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.	22
12115694	2002	Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.	22

Citation

Dessen P

SLC32A1 (solute carrier family 32 member 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73393