SLC38A9 (solute carrier family 38 member 9)

2014-11-01  

Identity

HGNC
LOCATION
5q11.2
LOCUSID
ALIAS
URLC11
FUSION GENES

Other Information

Locus ID:

NCBI: 153129
MIM: 616203
HGNC: 26907
Ensembl: ENSG00000177058

Variants:

dbSNP: 153129
ClinVar: 153129
TCGA: ENSG00000177058
COSMIC: SLC38A9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177058ENST00000318672Q8NBW4
ENSG00000177058ENST00000318672A0A024QZR9
ENSG00000177058ENST00000396865Q8NBW4
ENSG00000177058ENST00000396865A0A024QZR9
ENSG00000177058ENST00000416547B3KVK8
ENSG00000177058ENST00000502247D6RHW0
ENSG00000177058ENST00000503817D6RER8
ENSG00000177058ENST00000503891E7ESU6
ENSG00000177058ENST00000505563D6RBB9
ENSG00000177058ENST00000505708D6RHF5
ENSG00000177058ENST00000506624D6RDH2
ENSG00000177058ENST00000507109D6RDH2
ENSG00000177058ENST00000508124D6RE72
ENSG00000177058ENST00000511233D6R9Q7
ENSG00000177058ENST00000512208D6RG31
ENSG00000177058ENST00000512595Q8NBW4
ENSG00000177058ENST00000513275D6RIW7
ENSG00000177058ENST00000513993D6R9X0
ENSG00000177058ENST00000515629Q8NBW4

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
mTOR signaling pathwayKEGGko04150
mTOR signaling pathwayKEGGhsa04150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
328689262020Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.24
328689262020Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9.24
301812602018Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.70
301812602018Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.70
290539702017mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.229
290539702017mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient.229
255611752015SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.347
255679062015Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.432
259636552015Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.155
255611752015SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.347
255679062015Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1.432
259636552015Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.155
247627462014New genetic biomarkers predicting azathioprine blood concentrations in combination therapy with 5-aminosalicylic acid.2
247627462014New genetic biomarkers predicting azathioprine blood concentrations in combination therapy with 5-aminosalicylic acid.2

Citation

Dessen P

SLC38A9 (solute carrier family 38 member 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73429/gene-explorer/favicon/gene-fusions-explorer/