SLC6A7 (solute carrier family 6 member 7)

2014-11-01 Affiliation

Identity

HGNC

SLC6A7

LOCATION

5q32

LOCUSID

6534

ALIAS

PROT

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 6534
MIM: 606205
HGNC: 11054
Ensembl: ENSG00000011083

Variants:

dbSNP: 6534
ClinVar: 6534
TCGA: ENSG00000011083
COSMIC: SLC6A7

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000011083	ENST00000230671	Q99884
ENSG00000011083	ENST00000524041	E5RJL1

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
SLC-mediated transmembrane transport	REACTOME	R-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	REACTOME	R-HSA-425366
Na+/Cl- dependent neurotransmitter transporters	REACTOME	R-HSA-442660
Metabolism	REACTOME	R-HSA-1430728
Metabolism of amino acids and derivatives	REACTOME	R-HSA-71291
Creatine metabolism	REACTOME	R-HSA-71288
Metabolism of polyamines	REACTOME	R-HSA-351202

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20424473	2010	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	0
20431603	2010	A new association between polymorphisms of the SLC6A7 gene in the chromosome 5q31-32 region and asthma.	7
20431603	2010	A new association between polymorphisms of the SLC6A7 gene in the chromosome 5q31-32 region and asthma.	7
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20424473	2010	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	0
20431603	2010	A new association between polymorphisms of the SLC6A7 gene in the chromosome 5q31-32 region and asthma.	7
20431603	2010	A new association between polymorphisms of the SLC6A7 gene in the chromosome 5q31-32 region and asthma.	7
19874574	2009	Genetical genomic determinants of alcohol consumption in rats and humans.	107
19874574	2009	Genetical genomic determinants of alcohol consumption in rats and humans.	107

Citation

Dessen P

SLC6A7 (solute carrier family 6 member 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73478