SLC9C1 (solute carrier family 9 member C1)

2014-11-01  

Identity

HGNC
SLC9C1
LOCATION
3q13.2
LOCUSID
285335
ALIAS
NHE,NHE-10,SLC9A10,sperm-NHE

Other Information

Locus ID:

NCBI: 285335
MIM: 612738
HGNC: 31401
Ensembl: ENSG00000172139

Variants:

dbSNP: 285335
ClinVar: 285335
TCGA: ENSG00000172139
COSMIC: SLC9C1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172139ENST00000305815Q4G0N8
ENSG00000172139ENST00000471295F8WCJ0
ENSG00000172139ENST00000486574C9J3M6
ENSG00000172139ENST00000487372Q4G0N8

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351

References

Pubmed IDYearTitleCitations
334628062021The sodium/proton exchanger SLC9C1 (sNHE) is essential for human sperm motility and fertility.18
334628062021The sodium/proton exchanger SLC9C1 (sNHE) is essential for human sperm motility and fertility.18
230001552012Role of the Na(+)/H(+) exchanger on the development of diabetes mellitus and its chronic complications.3
230001552012Role of the Na(+)/H(+) exchanger on the development of diabetes mellitus and its chronic complications.3
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

SLC9C1 (solute carrier family 9 member C1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73502