ACOT7 (acyl-CoA thioesterase 7)

2003-05-01  

Identity

HGNC
LOCATION
1p36.31
LOCUSID
ALIAS
ACH1,ACT,BACH,CTE-II,LACH,LACH1,hBACH
FUSION GENES

Other Information

Locus ID:

NCBI: 11332
MIM: 602587
HGNC: 24157
Ensembl: ENSG00000097021

Variants:

dbSNP: 11332
ClinVar: 11332
TCGA: ENSG00000097021
COSMIC: ACOT7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000097021ENST00000361521O00154
ENSG00000097021ENST00000377842O00154
ENSG00000097021ENST00000377845O00154
ENSG00000097021ENST00000377855O00154
ENSG00000097021ENST00000377860O00154
ENSG00000097021ENST00000418124O00154
ENSG00000097021ENST00000473466K7EKP8
ENSG00000097021ENST00000545482O00154
ENSG00000097021ENST00000608083O00154

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Fatty acid elongationKEGGko00062
Biosynthesis of unsaturated fatty acidsKEGGko01040
Fatty acid elongationKEGGhsa00062
Biosynthesis of unsaturated fatty acidsKEGGhsa01040
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Fatty Acyl-CoA BiosynthesisREACTOMER-HSA-75105

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385028672024USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis.0
385028672024USP3 promotes cisplatin resistance in non-small cell lung cancer cells by suppressing ACOT7-regulated ferroptosis.0
352158352022Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication.2
352158352022Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication.2
324691712020Interaction between ACOT7 and LncRNA NMRAL2P via Methylation Regulates Gastric Cancer Progression.11
324691712020Interaction between ACOT7 and LncRNA NMRAL2P via Methylation Regulates Gastric Cancer Progression.11
316400822019Expression level of ACOT7 influences the prognosis in acute myeloid leukemia patients.10
316400822019Expression level of ACOT7 influences the prognosis in acute myeloid leukemia patients.10
284724012017WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms.5
285181462017Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway.22
284724012017WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms.5
285181462017Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway.22
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.7
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.17
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.7

Citation

Dessen P

ACOT7 (acyl-CoA thioesterase 7)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/740/gene-fusions-explorer/meetings/css/lib/bootstrap.min.css