SSNA1 (SS nuclear autoantigen 1)

2014-11-01  

Identity

HGNC
SSNA1
LOCATION
9q34.3
LOCUSID
8636
ALIAS
N14,NA-14,NA14
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8636
MIM: 610882
HGNC: 11321
Ensembl: ENSG00000176101

Variants:

dbSNP: 8636
ClinVar: 8636
TCGA: ENSG00000176101
COSMIC: SSNA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000176101ENST00000322310O43805
ENSG00000176101ENST00000322310A0A024R8G6
ENSG00000176101ENST00000464553A0A087WV26

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Anchoring of the basal body to the plasma membraneREACTOMER-HSA-5620912
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
Regulation of PLK1 Activity at G2/M TransitionREACTOMER-HSA-2565942
Centrosome maturationREACTOMER-HSA-380287
Recruitment of mitotic centrosome proteins and complexesREACTOMER-HSA-380270
Loss of proteins required for interphase microtubule organization from the centrosomeREACTOMER-HSA-380284
Loss of Nlp from mitotic centrosomesREACTOMER-HSA-380259
AURKA Activation by TPX2REACTOMER-HSA-8854518

References

Pubmed IDYearTitleCitations
375001342023SSNA1 Promotes Hepatocellular Carcinoma Metastasis Via STAT3/EMT Induction.0
375001342023SSNA1 Promotes Hepatocellular Carcinoma Metastasis Via STAT3/EMT Induction.0
349709642021SSNA1 stabilizes dynamic microtubules and detects microtubule damage.9
349709642021SSNA1 stabilizes dynamic microtubules and detects microtubule damage.9
253906462014Spastin-interacting protein NA14/SSNA1 functions in cytokinesis and axon development.14
253906462014Spastin-interacting protein NA14/SSNA1 functions in cytokinesis and axon development.14
220081822011Characterization of the structure and self-recognition of the human centrosomal protein NA14: implications for stability and function.5
220081822011Characterization of the structure and self-recognition of the human centrosomal protein NA14: implications for stability and function.5

Citation

Dessen P

SSNA1 (SS nuclear autoantigen 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74260