STYX (serine/threonine/tyrosine interacting protein)

2014-11-01  

Identity

HGNC
STYX
LOCATION
14q22.1
LOCUSID
6815
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6815
MIM: 615814
HGNC: 11447
Ensembl: ENSG00000198252

Variants:

dbSNP: 6815
ClinVar: 6815
TCGA: ENSG00000198252
COSMIC: STYX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198252ENST00000354586Q8WUJ0
ENSG00000198252ENST00000354586A0A024R641
ENSG00000198252ENST00000442123Q8WUJ0
ENSG00000198252ENST00000442123A0A024R641

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
322391812020STYX/FBXW7 axis participates in the development of endometrial cancer cell via Notch-mTOR signaling pathway.8
322391812020STYX/FBXW7 axis participates in the development of endometrial cancer cell via Notch-mTOR signaling pathway.8
309817572019Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer.12
309817572019Pseudophosphatase STYX promotes tumor growth and metastasis by inhibiting FBXW7 function in colorectal cancer.12
280078942017The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.14
284084852017STYX: a versatile pseudophosphatase.8
280078942017The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.14
284084852017STYX: a versatile pseudophosphatase.8
238472092013Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.25
238472092013Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.25
193696472009Identification of potentially damaging amino acid substitutions leading to human male infertility.8
193696472009Identification of potentially damaging amino acid substitutions leading to human male infertility.8

Citation

Dessen P

STYX (serine/threonine/tyrosine interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74349